In the gathering pipeline, the velocity and pressure of the oil-water two-phase flow through the elbow will change, which will increase the corrosion degree of the elbow and lead to frequent accidents caused by corrosion of the elbow. Taking water as discrete phase, the flow state in pipeline is numerically simulated by the combination of RNG turbulence model and DPM model. The variation law of pipeline corrosion influence factor is obtained, and the simulation data is processed by origin software and analyzed by orthogonal test method. The results show that the different pipeline parameters have different effects on cavitation corrosion rate. Among them, the pipe diameter has the greatest influence, the mass flow rate of water droplet particles, the inlet velocity of the fluid, and the bending angle of the pipe are the second, and the bending diameter ratio has the least influence on the cavitation corrosion rate.The research results can provide the technical support for the design and operation management of the gathering pipeline.